Palmitoylethanolamide (PEA) is an endogenous fatty acid amide produced naturally by the body in response to stress and inflammation. It plays a regulatory role in the nervous and immune systems, helping maintain balance in inflammatory signalling.
Rather than acting as a numbing agent, PEA works by supporting the body’s own regulatory pathways that influence nerve sensitivity and inflammatory tone.
In cancer-care settings, PEA is commonly used to support:
Neuro-inflammatory regulation
Peripheral nerve comfort
Balanced mast-cell activity
Recovery from treatment-related nerve stress
Ongoing nervous system stability
Its excellent tolerability makes it suitable for longer-term use as part of a structured support plan. PEA is often used as a foundational compound in protocols addressing chemotherapy-related nerve symptoms.